QUANTITATIVE MASS SPECTROMETRY ANALYSIS REVEALS SIMILAR SUBSTRATE CONSENSUS MOTIF FOR HUMAN MPS1 KINASE AND PLK1.

Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1.

BACKGROUND: Members of the Mps1 kinase family play an essential and evolutionarily conserved role in the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures accurate chromosome segregation during mitosis.Human Mps1 (hMps1) is highly phosphorylated during mitosis and many phosphorylation sites have been identified.However, the u

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Recurrent priapism in the setting of cannabis use

Abstract Priapism (persistent and painful erection of the penis) is a notable urological emergency, with over 90% of those remaining erect for 24 h losing sexual function.Drug-induced priapism is common in the adult population, with intracavernosal injectables Equine Grooming for erectile dysfunction topping the list.A variety of illicit drugs asso

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Recurrent priapism in the setting of cannabis use

Abstract Priapism (persistent and painful erection of the penis) is a notable urological emergency, with over 90% of those remaining erect for 24 h losing sexual function.Drug-induced priapism is common in the adult population, with intracavernosal injectables Equine Grooming for erectile dysfunction topping the list.A variety of illicit drugs asso

read more